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Steve Nissen Articles

PlayLepodisiran: What progress towards Lp(a) reduction?

Lepodisiran: What progress towards Lp(a) reduction?

Lepodisiran (LY3819469) is a short interfering RNA (siRNA) targeted at the mRNA for apolipoprotein A (apoA) – an essential component of lipoprotein a (Lp(a)). Elevated levels of Lp(a) are associated with atherosclerotic cardiovascular disease (ASCVD) and aortic stenosis, and Lp(a) measurement is recommended at least…

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Bempedoic acid: A CLEAR story

Bempedoic acid: A CLEAR story

Reports from the 19th Virtual Closed Scientific Expert Meeting of the Editorial Board  Steven Nissen

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siRNA-mediated lowering of Lp(a) by SLN360

siRNA-mediated lowering of Lp(a) by SLN360

Reports from the 17th Virtual Closed Scientific Expert Meeting of the Editorial Board  Steve Nissen 

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