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Steve Humphries Articles

PlayVerve-101: Where are we up to with PCSK9 gene editing?

Verve-101: Where are we up to with PCSK9 gene editing?

VERVE-101 is a novel CRISPR base editing agent designed to knock out expression of the PCSK9 gene by changing a single DNA base, thereby turning off PCSK9 protein production in hepatocytes and lowering LDL-C. VERVE-101 consists of an mRNA for an adenine base editor and…

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