PACMAN-AMI: new data on lesion-level effects of lipid lowering AT-TARGET-IT shows reduced CV risk with early PCSK9i in ACS Real world ischaemic event reduction with PCSK9i mAbs Inclisiran role in plaque stabilisation Discontinuing PCSK9i leads to increased MACE V-MONO trial of inclisiran monotherapy meets primary endpoints

Jan Albert Kuivenhoven Articles

Intracellular actions of PCSK9

Reports from the 7th Expert Meeting of PCSK9 Forum The hepatic extracellular function of PCSK9 in inhibiting the LDL receptor is now well established. With the development of novel agents that block PCSK9 synthesis upstream, investigation of intracellular actions of PCSK9 is a new focus…

Posted on 28 September 2017 | Posted by Jan Albert Kuivenhoven | Posted in Webcasts, 7th Closed Scientific Expert Meeting of the Editorial Board

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PCSK9 Education and Research Forum is a not-for-profit organisation established by leading researchers in the fields of atherosclerosis, lipids and cardiovascular disease. Our mission is to raise awareness and knowledge of the significant role played by PCSK9 in lipid metabolism and its value as a novel therapeutic target.

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