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Post hoc analysis: alirocumab benefits HeFH and T3HLP patients Results from the German MILOS cohort demonstrate real-world effectiveness and safety of bempedoic acid PCSK9 inhibitors are unlikely to contribute to mood disorders PCSK9 inhibitors may be effective treatment for PAD PACMAN-AMI: new data on lesion-level effects of lipid lowering AT-TARGET-IT shows reduced CV risk with early PCSK9i in ACS

Latest News Updates

AHA Scientific Sessions 2022

5-7 November, Chicago, IL, USA (Hybrid Meeting)

ORION-3: 4-year data with inclisiran

ORION-3: 4-year data with inclisiran

News from the American Heart Association Scientific Sessions 2022 Results from ORION-3, the 4-year open-label extension of the ORION-1 trial (1), showed sustained reduction in LDL cholesterol levels with a favourable safety profile. ORION-1 (ClinicalTrials.gov, NCT02597127) randomized 501 subjects with atherosclerotic cardiovascular disease (ASCVD) or…

Posted on 15 November 2022 | Posted in News, AHA Scientific Sessions 2022

OCEAN(a)-DOSE: Olpasiran shows substantial lipoprotein(a) reduction

OCEAN(a)-DOSE: Olpasiran shows substantial lipoprotein(a) reduction

News from the American Heart Association Scientific Sessions 2022 In the OCEAN(a)-DOSE trial, treatment with olpasiran, a small interfering RNA (siRNA) agent targeting apolipoprotein(a), reduced lipoprotein(a) [Lp(a)] by up to 100%. The study was simultaneously published in the New England Journal of Medicine (1). In…

Posted on 15 November 2022 | Posted in News, AHA Scientific Sessions 2022

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Unless otherwise indicated, opinions expressed in the PCSK9 Education and Research Forum are those of the contributors. All patients should discuss their medication with their healthcare professional. Although every effort is made to ensure accuracy and avoid mistakes, no liability on the part of the PCSK9 Forum, the editors or the editorial board is accepted for the consequences of any misleading or inaccurate information.

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