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PCSK9 – targeted therapies: new hope for homozygous FH?

PCSK9 – targeted therapies: new hope for homozygous FH?

Homozygous familial hypercholesterolemia (HoFH) is a rare life-threatening condition which is defined clinically by plasma cholesterol levels usually exceeding 13 mmol/L (500 mg/dL), with extensive cutaneous or tendon xanthomas and premature atherosclerosis and cardiovascular disease.1 Historically, HoFH is thought to affect about 1 in a…

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